Modeling fibroblast cells movement

Abstract

Inspired by the success of Mathematical and Computational modeling in different fields, we study the movement of fibroblast cells and how they contribute to tissue fibrosis. With this approach, we can quantify the magnitude and scale of the mechanisms that drive these cell’s movement, and identify the conditions that lead to an increase of cell density. This approach allows us to optimize the costs and time of in-vitro experiments, while reproducing conditions which could be linked to fibrosis, and potentially elucidate possible paths to the development of novel treatments for fibrosis.