Control of Cardiac Alternans Using Electrical Boundary Pacing and Spatially Distributed Perturbation Control

Authors

  • Azzam Hazim University of Alberta
  • Youssef Belhamadia University of Alberta
  • Stevan Dubljevic University of Alberta

Abstract

Electrical alternans in cardiac Action Potential Duration (APD) have been shown to be a precursor to arrhythmias and sudden cardiac death (SCD). In this work, we study the annihilation of alternans based on an eletro-mechanical model and using boundary pacing and spatially distributed control. The mathematical equations are based on the Nash-Pafilov model (NP), This model includes an additional variable to represent the active stress which is responsible for mechanical deformation and is coupled to the stress equilibrium equation, describing the tissue’s mechanics model. An algorithm that combines boundary pacing control and spatially distributed control to annihilate the alternans is implemented using NP model in the limit of small deformation.

Downloads

Published

2019-06-20

How to Cite

[1]
A. Hazim, Y. Belhamadia, and S. Dubljevic, “Control of Cardiac Alternans Using Electrical Boundary Pacing and Spatially Distributed Perturbation Control”, CMBES Proc., vol. 37, Jun. 2019.

Issue

Vol. 37 (2014)

Section

Academic